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The islet-related autoantibodies are negative, and increasing levels of serum pancreatic enzyme are often observed [4]

For instance, salinity stress disrupts maizes biochemical and physiological processes, leading to cellular imbalances, ionic disturbances, impaired nitrogen fixation and respiration, and the inhibition of crucial metabolic enzymes involved in photosynthesis (Iqbal et al., 2020)

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It also stimulates the overexpression of the transient receptor potential melastatin 2 (TRPM2) ion channels, triggering macrophage activation, leading to a systemic immune response

Pregnancy and breastfeeding Small clinical studies suggest that ALA may be safe during pregnancy at doses up to 600mg/day for several weeks, with no serious adverse effects reported.40 However, larger, long-term studies are lacking, and there is no reliable safety data for breastfeeding