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Insulin resistance: Patients with metabolic dysfunction, including pre-diabetes or difficulty managing blood sugar, tend to see meaningful improvement in metabolic markers alongside body composition changes

24 Although we recruited dementia patients with cerebrovascular evidence, who were already treated with donepezil, we cannot definitively conclude that study subjects included pure vascular dementia

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Menopausal status did not meaningfully alter treatment response, as seen here: What we know about hormone therapy and weight-loss response Menopausal hormone therapy is not indicated for weight loss