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The letters say the telehealth companies claim their products contain the same active ingredient as Wegovy, Ozempic, Mounjaro and Zepbound

GolperTAWolfsonMAhmadSHirschbergRKurtinPKatzLAet alMulticenter trial of L-carnitine in maintenance hemodialysis patients

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Preclinical studies indicate that these drugs shift macrophage polarization from a pro-inflammatory M1 to an anti-inflammatory M2 phenotype through HIF-1 downregulation and AMPK activation, enhancing tissue repair and reducing oxidative stress (95, 96)

Some patients may experience mood changes, including depression or anxiety, particularly during the initial weeks of treatment