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This effect was reversed by deletion of NOX1-4, NOX3 alone, or treatment with the ROS scavenger N-acetyl cysteine (NAC)

however, senescent cells infamously secrete high levels of pro-inflammatory cytokines, chemokines, and extracellular matrix-degrading proteins that negatively impact the extracellular environment and induce spread of senescence to non-senescent cells (2932)

Protein bands were quantified by densitometry using Image Lab v4.1 software (Bio-Rad, UK)

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Whilst the literature acknowledges that both scientific inquiry and technological innovation are crucially entangled with urbanization (Palmini, Cugurullo, 2023) and have been so for centuries , less attention has been paid to the correlation amongst technology (here understood as the force driving mankind interpretation of reality: Severino, 2021), scientific specialization (Pitari, 2019), and the consolidation of urban planning as a technical domain