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Concurrently, the linker, a cyclic diamine, was modified with acryloyl chloride, and these two units were subsequently assembled, and the phosphate-moiety further deprotected to form the desired nucleotide-based inhibitors as 2 and 3-isomers (Fig
Ippolito, L., Giannoni, E., Chiarugi, P
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Bioassays were undertaken by the same observer to minimize any observational discrepancies
Use a standard U-100 insulin syringe for injecting
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