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At this concentration, individual dose volumes on a standard U100 insulin syringe are: The 0.25mg and 0.5mg early-escalation doses produce sub-30-unit volumes that benefit from a 0.3mL low-dead-space U100 insulin syringe (or 0.5mL syringe) for precise volume control

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Available from: Accessed: 19 Sep 2025 Jastreboff AM, Kaplan LM, Fras JP et al (2023) Triplehormone-receptor agonist retatrutide for obesity: a phase 2 trial