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The GPX1 gene is located on chromosome 3p21.31 and is composed of 2 exons that generate five alternatively spliced mRNAs due to the use of alternative splice acceptor sites in the 3-exon

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(43) Patient Safety and Side Effects Gastrointestinal Issues: Common side effects include nausea, diarrhea, constipation, and vomiting, particularly during dose escalation