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Tubular epithelial cell HMGB1 promotes AKI-CKD transition by sensitizing cycling tubular cells to oxidative stress: A rationale for targeting HMGB1 during AKI recovery

Rybelsus commonly causes nausea, vomiting, and abdominal discomfort, particularly during the initial weeks of treatment

Patients often find it easier to stick to portion-controlled meals and avoid late-night snacking or emotional eating

Some are engineered to respond to physiological cues, such as pH or enzymatic activity, which allow for site-specific release of bioactive compounds or secondary delivery systems that mediate therapeutic effects (Ma Y