Clinical analysis of therapeutic effect of levocarnitine on dialysis patients
Burgerstein L-Carnitin (100 Stk) Wichtig fr den Energiestoffwechsel und die Ausdauerleistung bei Sportlern
Introduction Carnitine (-hydroxy--trimethylammonium butyrate) is a water-soluble quaternary amine with several vital metabolic functions, with the main one being the transport of long-chain fatty acids across the inner mitochondrial membrane, thus providing a substrate for -oxidation and energy production [1]
Bellinghieri G, Santoro D, Calvani M, Mallamace A, Savica V: Carnitine and hemodialysis
Third, TMAO may potentially disrupt the equilibrium of renal electrolytes and water transport by inhibiting sodium and water reabsorption in the kidneys, resulting in sodium retention and volume expansion, characteristic features of chronic kidney disease ( Figure 4 Besides, TMAO may directly harms kidney structure, causing glomerular hypertrophy, tubulointerstitial fibrosis, and renal inflammation in animals, which promoting the progression of CKD