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As rats on the fcHF diet lacked the sugar component and consumed more calories from fat compared to rats on the fcHFHS diet, and fat intake was the most inhibited after MTII administration, these data point toward an important role for diet composition and particularly the fat content in the diet in sensitivity to melanocortins

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doi:10.1136/bmj-2023-078225 Baxter SM, Lund LC, Andersen JH, Brix TH, Hegeds L, Hsieh MH, Su CT, Cheng MC, Chang ZC, Lai EC, Hussain S, Chu C, Gomes T, Antoniou T, Eskander A, Bouck Z, Tadrous M, Bea S, Choi EY, Shin JY, Modig K, Talbck M, Ljung R, Gulseth HL, Karlstad , Hicks B, Pottegrd A

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