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Its history began with a breakthrough by a research team at the University of Texas, USA, in 2017.At that time, NNMT was recognized as a key enzyme in cellular metabolism and energy homeostasis, highly active in adipose tissue and closely linked to obesity, type 2 diabetes, and other metabolic diseases

"Since that link exists, we thought that maybe drugs that cause people to lose weight could reduce cancer risk." It stands to reason that maintaining a healthy body weight and regular exercise are known to have protective effects against the disease

Sottero B, Gargiulo S, Russo I, Barale C, Poli G, Cavalot F

Compounding pharmacies assign beyond-use dates for a reason

GHK naturally occurs in human plasma at approximately 200 ng/mL in young adults, declining significantly with age (PMID 29986520)