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The mGLP1-DARPin-1 fusion protein that was more resistant to DPP-IV cleavage can be used as a long-lasting injectable form of GLP-1, and the mGLP1-DARPin-2 fusion protein that was resistant to both DPP-IV and trypsin cleavage can be used as a candidate for oral delivery of GLP-1 bioencapsulated in plant cells

No tolerance developed to this protective effect, which appeared to be mediated by (1) the activation of 5-HT 1A receptors, as it was antagonized by the administration of WAY100635 30 min before stress exposure

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Correa-Perez, A