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ROS-induced damage to DNA, proteins, and lipids can directly lead to cell death, but it also promotes microglial activation and the release of pro-inflammatory cytokines, further exacerbating neurodegeneration (Tfilin et al., 2023)

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p = 0.04), indicating a notable advantage of Tirzepatide over Semaglutide in reducing HbA1c levels, with a large difference in efficacy between the two medications (Figure 10)

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