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Losing 25 pounds or more can sometimes reveal hollowing through the cheeks, flattening of the midface, temple deflation, or subtle sagging along the lower face

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This protein then metabolizes x-gal to produce a blue colour

Some patients may experience temporary sleep disruption during periods of active weight loss, though evidence for this specific to tirzepatide is limited

However, any symptom that is persistent, severe, or accompanied by other warning signs should not be self-managed without professional assessment