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Cancer 21 , 669680 (2021)

This research showed that GSH supplementation of amino acids (including L-glycine) and micronutrients (including vitamin C, vitamin E, and magnesium), as well as specific dietary patterns (vegetarian, the Mediterranean diet, and the DASH diet) had the potential to raise glutathione concentrations, which in turn slowed the rate of tissue deterioration

However, the presence of conserved amino acids in the shared motif between Zot and zonulin lead these researchers to synthesize an octapeptide, now known as LA, with the same amino acid sequence as the NH 2 -terminus of human fetal zonulin, positions 815 (7)

The potential for tachyphylaxis or tolerance development requires monitoring with chronic peptide therapy

Kou et al