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Studies conducted in mice and human foreskin fibroblasts have revealed that S-acetyl-glutathione molecules are taken up directly by cells with subsequent conversion to glutathione by cleavage of the acetyl bond within the cell

, myeloperoxidase, leukotriene B4, tromboxane B2) (44), interacts with prostaglandin-dependent pathways (45, 46), has a direct protective and proliferative effect on target cells (18, 19), and modulates the release of nitric oxide (27)