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While stress + UFe treatment resulted in moderate enrichment of key discriminative metabolites, CK-stress samples consistently exhibited the lowest normalized values, underscoring the suppressive effect of saline-alkali stress in the absence of nanoparticles intervention

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48 Similarly, among obese individuals without diabetes, semaglutide use was shown to increase the risk of developing GI adverse events by 1.59 times compared with the control group

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This wide receptor coverage makes it a foundational tool for probing melanocortinreceptor binding, Gproteincoupled cAMP signalling, and downstream transcriptional responses, as well as for comparative selectivity studies against more receptorselective analogues