Option 1: Stay on the Max Dose for Longer One approach for patients who reach weight loss plateaus on the maximum weekly dose of GLP-1s is to simply give it more time
Patients may still experience nausea, diarrhoea, constipation, vomiting, indigestion or reflux, especially when starting treatment or moving through dose changes
For example, GIP inhibits the release of gastrin, show glucose-dependent glucagonotropic activity, and regulate signaling pathways in the brain and adipose tissues involved in energy homeostasis
Simple lifestyle measures, such as wearing loose-fitting clothing, changing out of wet swimsuits promptly, and using gentle, fragrance-free soaps, can also help reduce irritation and recurrent episodes
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