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doi: 10.1136/jcp.2009.072561 114 KomaroffAL

Gastrointestinal symptoms are the most frequently reported adverse effects and may include: Nausea and vomiting often severe and persistent, potentially leading to dehydration and, in some cases, acute kidney injury (particularly if you have existing kidney problems) Abdominal pain or discomfort ranging from mild cramping to significant pain Diarrhoea which may be frequent and watery Loss of appetite more pronounced than usual Bloating and indigestion due to delayed gastric emptying Hypoglycaemia (low blood sugar) is another concern, particularly if you are taking other diabetes medications such as insulin or sulphonylureas