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Effect of pomegranate extract on plasma TMAO response Ten of 16 participants exhibited lower TMAO AUC following pomegranate intervention compared with placebo (Figure 5)

These findings underscore the translational relevance of rodent models and highlight potential species-specific differences, particularly in cortical GLP-1R expression relevant to executive function and craving control [25]

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35 Oral GLP-1 receptor agonists are also under development

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