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The functional diversity of Aurora kinases: a comprehensive review

A.Abdel-RahmanH

PlexusDx patients should understand the interaction landscape before reaching for the medicine cabinet

For example, during excitotoxicity, the intracellular Ca 2+ concentration is abnormally elevated, leading to an excessive release of glutamate and a massive influx of Ca 2+ into the postsynaptic neuron, triggering an imbalance in Ca 2+ homeostasis and resulting in intracellular Ca 2+ overload

In agreement with previous evidence from genetic models, these data show that chronic modulation of IGF-1R signaling may be most well suited for targeting aging in females 6,7,8 , rather than males