[DOI] [PMC free article] [PubMed] [Google Scholar] 93.Aroda V.R., Rosenstock J., Wysham C., Unger J., Bellido D., Gonzalez-Galvez G
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Next Steps: Data Gaps: Clinical human safety data is currently limited to retrospective studies (e.g., sample size of 12) Nih
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Notably, this review synthesizes the molecular mechanisms through which exercise mitigates atherosclerosis, encompassing the regulation of exercise-induced factor expression, promotion of iWAT browning and BAT activation, elevation of blood lactate concentration to facilitate lactylation modification, and suppression of diverse cell death pathways