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The BACH1/NRF2 axis has been extensively studied in Down syndrome and BACH1 encoded on chromosome 21 is known to negatively regulate NRF2 [25]

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Endogenous and exogenous fatty acid oxidation (FAO) were evaluated by measuring OCR in the presence or absence of etomoxir (a FAO inhibitor) or palmitate, respectively

Acta Haematologica 103:37, 2000

Am Fam Physician 76:3916 Wu Y, Zhang X, Bardag-Gorce F, Robel RC, Aguilo J, Chen L, Zeng Y, Hwang K, French SW, Lu SC, Wan YJ (2004) Retinoid X receptor alpha regulates glutathione homeostasis and xenobiotic detoxification processes in mouse liver