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Therefore, the authors postulated that the GLP-1-induced vasodilation might reduce total peripheral resistance, leading to a reflex tachycardia [39]

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Other studies focusing on immune checkpoint inhibitors for acral melanoma identified low objective response rates [100,101,102,103,104,105,106,107], although these studies involved relatively small sample sizes of acral melanoma (639 patients), and the numbers of NAM cases included are not available