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With a tally of 17-1, the advisory committee (adcomm) determined that there was not substantial evidence that NurOwn, a cell therapy made up of mesenchymal stromal cells secreting neurotrophic factors (MSC-NTF), was an effective treatment for patients with mild to moderate ALS

Self-administration without clinical oversight removes the safety layer that makes the protocol viable

Furthermore, increased astrocytic LTF appears to reduce A burden in APP/PS1 AD mice (Fan et al., 2024)

Conventional treatment usually focuses on suppressing symptoms with topical medications, oral antibiotics, or laser therapy