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N Engl J Med 6 392(10):958971 Wharton S, Blevins T, Connery L, Rosenstock J, Raha S, Liu R, Ma X, Mather KJ, Haupt A, Robins D, Pratt E, Kazda C, Konig M

demonstrated no improvement in PFS or OS in breast cancer patients treated with the combination of sunitinib and docetaxel compared to docetaxel alone in an open-label, randomized, phase III trial (Curigliano et al., 2013)

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Table 5: Incidence of Severe Hypoglycemia* and Hypoglycemia with Glucose 55% were reported in 0.4% of placebo-treated patients and 1.3% of dapagliflozin 10 mgtreated patients

So you need to have good zinc status, good iron status, you good thyroid status and all kinds of stuff like that