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2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)

Injecting just before bed, when endogenous GH secretion is about to peak, synchronizes the peptide's action with your body's existing rhythm

Source - How different to other pens (FlexTouch vs SDD) FlexTouch pens are the standard Wegovy pen and are currently used for the lower doses (0.25mg - 2.4mg)