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The aim of this paper is to review the role of ROS in normal physiological functions, ROS-mediated cellular signaling, and the role of oxidative stress in various chronic diseases and aging

& Gori Savellini, G

This may occur as part of natural metabolism (158) or when microbes are exposed to drugs that undergo aberrant reactions, such as metronidazole (159161)

Figure 6 Contrary to the oncogenic implications outlined earlier, the upregulation of SLC7A11 can also induce apoptotic cell death in cancer cells under conditions