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95% CI 0.160.33) compared with the non-GLP-1 RAs group

Results Later Period Baseline Demographic and Clinical Characteristics SGLT2i Cohort After applying all inclusion and exclusion criteria, the new-user cohort included 94,080 patients with a mean age of 73.1 (SD 8.9) years, of whom 47.0% were female, 56.1% were white, 46.0% had obesity, and 26.0% were current smokers (Table 1)

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In addition, several dual GLP-1R-glucagon receptor co-agonists are under development, and their therapeutic potential for the treatment of T2D and obesity is being investigated in clinical trials (55, 90, 91, 92)

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