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Its active ingredient is tirzepatide, a synthetic drug that acts as a dual agonist for two hormones: GLP-1 and GIP

Commonly examined in studies involving cellular signalling and metabolic response pathways

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Senescent cells, which were originally thought quiescent, have more recently emerged as an active driver of tissue aging, secreting a number of proteases and cytokines, termed senescence-associated phenotype (SASP), which damage surrounding tissue [47]

For patients prescribed Wegovy in the UK, this involves following the recommended dose escalation schedule, starting at 0.25mg weekly and gradually increasing to the maintenance dose of 2.4mg over 16-20 weeks