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Khavinson et al

First-Line Treatments: Where OTC Antiperspirants Fall Short Clinical guidelines from the American Academy of Family Physicians (AAFP) and the International Hyperhidrosis Society recommend topical aluminum chloride hexahydrate (1520%) as a first-line option

Research on metabolic pathways in the disease is still ongoing

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Seiler A, Schneider M, Frster H et al (2008) Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death