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Currently, although it appears that the world is in the final stages of the COVID-19 pandemic, there exists no guarantee that hidden health-related concerns (especially those associated with psychosocial health) will not potentially appear or develop in the form of post-pandemic consequences, or that the world will not experience a similar health tragedy in the future

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Among these metabolites, butyrate plays a key role in maintaining intestinal barrier integrity by strengthening tight junction architecture and modulating its regulatory signaling pathways (168)