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doi:10.1038/ng.544

Intestinal neuroendocrine cells and goblet cells are mediators of IL-17A-amplified epithelial IL-17C production in human inflammatory bowel disease

Individual genetic differences in GLP1R (glucagon-like peptide-1 receptor) expression and function determine how sensitively your nervous system responds to semaglutide

This is largely attributable to GLP-1 and GIP receptor activity slowing gastric emptying and modulating hunger signals in the brain

Compared to an isocaloric control diet, the high carbohydrate-high calorie diet was safe, tolerable and effective in delaying weight loss and prolonging survival in the patients (Wills et al., 2014)