The Sun 2021 study used the APP/PS1 transgenic mouse model of Alzheimers disease, with intragastric administration of Dihexa at 1.44 mg/kg or 2.88 mg/kg once daily for three months (six to nine months of age in the APP/PS1 cohort)
doi: 10.1016/j.niox.2018.05.002
When nasal spray makes sense Choose nasal spray when: Severe needle phobia (can't overcome) Peptide proven effective nasally (PT-141, Semax) Convenience absolute priority Willing to pay 2-3x more for same effect Traveling frequently (easier to carry) Don't want injection marks Best candidates for nasal: PT-141 users (proven nasal efficacy) Semax/Selank users (designed for nasal) Needle-phobic individuals Infrequent users (as-needed dosing) Those who tried injection and hated it When injection is better Choose injection when: Want maximum efficacy Budget-conscious (2-3x less expensive) Using peptides designed for injection Need consistent results Long-term regular use planned Comfortable with needles (or can learn) Best candidates for injection: Growth hormone peptides (Ipamorelin, CJC-1295) Daily peptide protocols Cost-conscious users Those wanting proven delivery Comparison summary: Hybrid approach: Some use injection primarily Keep nasal spray for travel/convenience Example: Inject BPC-157 , nasal PT-141 Match delivery to peptide and situation See peptide injections guide for injection technique
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You may benefit from high-dose glutathione therapy if you experience chronic fatigue, frequent illness, brain fog, or signs of accelerated aging
