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Lastly, athletes wishing to explore NO enhancers are reminded that a good level of evidence exists for L-citrulline to improve exercise performance, and therefore may consider use of this supplement whilst the intricacies of CM supplementation are discovered (Gonzalez and Trexler 2020)

Declarations Acknowledgement The authors thank Dr

It is not intended for human ingestion, medical use, veterinary treatment, or any form of in vivo application

Lifestyle modificationweight loss, physical activity, and dietary changesremains the most effective evidence-based treatment for NAFLD as per NICE guidance

Studies show that the highest dose of semaglutide (2.4 mg weekly) leads to the greatest average weight loss of 15%