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Finally, amelioration of the G/F-actin ratio restores the disruption of the YAP signal induced by high glucose and upregulates the transcription factors Neurod1, Foxa1, and Foxa2, which are responsible for controlling L-cell differentiation [30] (Fig

When combined with semaglutide in CagriSema, results are comparable to Zepbound, though slightly lower in a head-to-head trial