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Its ergonomic shape and lightweight design make it easy to carry, while the wide mouth allows for effortless filling and cleaning

This becomes particularly relevant in obesity and metabolic medicine, where therapies may ultimately be prescribed for years potentially decades and reach millions of individuals globally

The most common adverse events are nausea and other gastrointestinal discomfort

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While this remains the usual strategy for patients when HbA 1c levels are very high, SGLT2 inhibitors [194] and GLP-1 receptor agonists [195] have demonstrated efficacy in patients with HbA 1c levels exceeding 75 mmol/mol (9%), with the additional benefits of weight reduction and reduced risk of hypoglycaemia