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however, we observed no effect of ML226 or ABHD11 depletion on expression of the OGDHc-E2 gene transcript ( DLST ), nor on OGDHc-E2 protein stability during a cycloheximide chase assay (Extended Data Fig

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By providing a robust intracellular antioxidant shield, glutathione helps stabilize hyper-reactive mast cells, making them less likely to release histamine in response to minor environmental triggers, thereby reducing the frequency of hives, flushing, and sudden allergic responses