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However, clinically significant improvements in overall glycemic control should not be expected during the initial month, as this dose is primarily intended for gastrointestinal adaptation rather than maximal therapeutic effect

Semaglutide, a newly available glucagon-like peptide receptor agonist, shows remarkable favorable effects in hemodialysis patients with obesity and type 2 diabetes

Kruse, T

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Mean weight reductions were: 15 mg dose: 20.9 percent 10 mg dose: 19.5 percent 5 mg dose: 15.0 percent Placebo: 3.1 percent At the highest dose, 57 percent of participants lost at least 20 percent of their body weight, and 36 percent lost at least 25 percent [2]