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Specific protein 1 (SP1)-mediated upregulation of PRDX6 expression also prevented iron overload by regulating iron metabolism, restoring SLC7A11 activity and GSH activity, and further promoting the increase in GPX4 expression to prevent ferroptosis-associated DN [238]

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Glutathione is a naturally occurring compound in the body and is generally considered safe for most people

The pair were among 50 athletes secretly flagged by the Athlete Biological Passport, and subsequently cleared as "normal"

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