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[DOI] [PubMed] [Google Scholar] 10.Andreadis AA

Disruption of this integrated network (e.g., via ferroptosis inhibitors targeting ACSL4/GPX4, anti-inflammatory agents blocking HMGB1/IL-33, or HIF modulators balancing hypoxia adaptation) can break the pathogenic cycle, highlighting the therapeutic potential of targeting the networks central nodes rather than individual pathways

JGH Open

Thus, he believes future successful prevention or treatment for Alzheimers will be a combination of medicationsdrugs that will work together to attack the various pathways of how Alzheimers occurs in individuals

PLoS One 11, e0165267