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[31] [32] However, in 2003-2012, the National Institutes of Health (NIH) sponsored a $30 million controlled trial of chelation therapy, conducted by their National Center for Complementary and Alternative Medicine (NCCAM)

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Individuals with B12 deficiency, which can occur due to dietary restrictions (e.g., vegan or vegetarian diets), gastrointestinal disorders affecting absorption, older age, or certain medical conditions that interfere with B12 absorption