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9 Challenges and limitations to compliance with GLP-1 RA therapy While GLP-1 RA therapies are highly effective for glycemic control and weight loss, real-world data indicate that many patients either discontinue or struggle to adhere to these treatments

Chronic administration of GLP1/E significantly improved also glucose handling, as compared with the vehicle-treated PWA group, whereas no glucoregulatory actions were detected in mice treated with the dual or triple agonist (Fig

CagriSema: Fixed-ratio combination of two separate molecules -- cagrilintide (long- acting amylin analog) and semaglutide (GLP-1 agonist) -- co-administered in a single weekly injection