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Preclinical literature reports the use of thymosin beta-4-related peptides in neural, vascular, cutaneous, and cardiovascular models, with histological, biochemical, and molecular analyses aimed at evaluating stress markers, cytoskeletal organization, and tissue response

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Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M

revealed that the LN microenvironment can reprogram cancer cells, leading to an elevation in interferon-induced gene signatures, which subsequently caused the upregulation of MHC class I and PD-L1 gene expression in cancer cells (57)

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