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Tolerability profile consistent with the incretin class, with gastrointestinal events most commonly reported in studies (e.g., nausea, diarrhoea, and constipation)

Although the safety of metformin use in early pregnancy has been tentatively affirmed, additional data are required to definitively confirm its safety profile

The kidnapping of mitochondrial function associated with the SARS-CoV-2 infection

Common gastrointestinal side effects include: Nausea and vomiting (affecting 1540% of patients, depending on the specific medication and dose) [13] [16] Diarrhoea (reported in 1030% of patients) Constipation (affecting 1020% of patients) Abdominal pain and discomfort Reduced appetite and early satiety Dyspepsia and gastro-oesophageal reflux symptoms These effects are generally dose-dependent and tend to improve over time as the body adjusts to the medication

As a medical school professor, this may be the most unexpected finding in metabolic medicine right now