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Beyond mediating outer mitochondrial membrane fusion, Mfn1/2 participates in mitophagy regulation, mitochondrial cristae remodeling, and facilitates stress-associated unfolded protein response (UPR) (Hu et al., 2019

A: DSIP is a naturally occurring peptide that works through endogenous sleep pathways rather than receptor binding, providing more physiologically relevant research models for sleep studies

Insurance coverage is expanding but remains more variable than semaglutide coverage, partly because tirzepatide has been on the market for less time

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doi: 10.1113/jphysiol.2014.282665