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These changes in the ultrastructure of rat testicular tissues indicated that the simulated high-altitude, low-pressure and hypoxic environment affects the tight junctions between rat Sertoli cells, mesenchymal cells and spermatogonia

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According to a study in the Journal of Neuropsychiatry , high doses of Vitamin B6, in particular, may exacerbate anxiety in susceptible individuals

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Transl Psychiatry 3:e220 Thomas RH, Foley KA, Mepham JR, Tichenoff LJ, Possmayer F, MacFabe DF (2010) Altered brain phospholipid and acylcarnitine profiles in propionic acid infused rodents: further development of a potential model of autism spectrum disorders