Within the class S4 of hormone and metabolic modulators of the WADA Prohibited List, 39% of the adverse analytical findings (AAF) reported in 2020 resulted from SERMs (tamoxifen and clomiphene) and another 29% from AIs (letrozole, anastrozole, exemestane, and adrostatrienedione) (World Anti-Doping Agency, 2022)
In addition, mitochondria are also the primary producers of intracellular reactive oxygen species (ROS), most of which originate from the mitochondrial respiratory chain [55]
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2011, Heidelberg: Springer Science+Business Media, LLC, 205-230.Hsp70: Anti-apoptotic and tumorigenic protein, Methods in Molecular Biology Proctor CJ, Lorimer IA: Modelling the role of the Hsp70/Hsp90 system in the maintenance of protein homeostasis
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