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An examination of the behavioral and neuropsychological correlates of three ADHD candidate gene polymorphisms (DRD4 7+, DBH TaqI A2, and DAT1 40 bp VNTR) in hyperactive and normal children followed to adulthood

Decreased relative CTC1 gene expression to 0.76

Sowers MR, Crawford S, McConnell DS, Randolph JF Jr, Gold EB, Wilkin MK, Lasley B

The cytokines TNF, IL-6, and chemokines activate cellular pathways such as the MAPK, and JAK/STAT pathways and activate TGF- receptors that promote inflammation and stimulate fibroblast/pericyte activation