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Of four RCTs included in this meta-analysis that assessed the effect of L-carnitine supplementation in patients with NAFLD/ NASH, three studies reported that L-carnitine does not significantly affect lipid profile (Hong et al., 2014
It is encountered by every individual at different junctures of their lives
The sterol regulatory element-binding protein (SREBP) family of transcription factors plays a crucial role in lipid metabolism by regulating the expression of a series of enzymes required for lipid synthesis, and nuclear fragments of transcriptionally active SREBPs (nSREBPs) are unstable, degraded by the ubiquitin-proteasome pathway
Horowitz, R.I
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